Nature, Published online: 27 February 2026; doi:10.1038/d41586-026-00621-w
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Patient leaflets on weight-loss injections state that gallstones are a "common" side effect, and in medical trials the injections also sometimes led to inflammation of the gallbladder. For example in Mounjaro, it has been reported this may affect up to 1 in 100 people.